Skip Navigation

This Article
Right arrow FREE Full Text (PDF) Freely available
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in ISI Web of Science
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to My Personal Archive
Right arrow Download to citation manager
Right arrow Search for citing articles in:
ISI Web of Science (20)
Right arrowRequest Permissions
Google Scholar
Right arrow Articles by Frayne, J.
Right arrow Articles by Hall, L.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by Frayne, J.
Right arrow Articles by Hall, L.
Social Bookmarking
Add to CiteULike   Add to Connotea   Add to Del.icio.us  
What's this?

Molecular Human Reproduction, Vol 4, 429-437, Copyright © 1998 by Oxford University Press

JOURNAL ARTICLE

Macaque MDC family of proteins: sequence analysis, tissue distribution and processing in the male reproductive tract

J Frayne, JA Jury, HL Barker, AC Perry, R Jones and L Hall
Department of Biochemistry, University of Bristol, School of Medical Sciences, UK.

A large number of sequence-related, cysteine-rich membrane proteins containing metalloproteinase-like and disintegrin-like domains (the MDC protein family) have been identified in mammalian tissues from a variety of species. Previous studies in the macaque (Macaca fascicularis) have led to the cDNA cloning and sequence analysis of a number of MDC proteins which are abundantly expressed in the male reproductive tract. We now describe the distribution of seven of these macaque MDC transcripts in a range of different tissues. This description includes a novel macaque testis-derived MDC, tMDC III, whose full-length sequence is reported for the first time. In addition, polyclonal antisera have been used to localize a number of these MDC proteins to spermatogenic cells in testis sections, and to demonstrate their processing on the sperm surface during epididymal transit.
Add to CiteULike CiteULike   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us    What's this?


This article has been cited by other articles:


Home page
 Biol. Reprod.Home page
T. Kim, J. Oh, J.-M. Woo, E. Choi, S. H. Im, Y. J. Yoo, D. H. Kim, H. Nishimura, and C. Cho
Expression and Relationship of Male Reproductive ADAMs in Mouse
Biol Reprod, April 1, 2006; 74(4): 744 - 750.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
J. Frayne, E. A.C. Hurd, and L. Hall
Human tMDC III: a sperm protein with a potential role in oocyte recognition
Mol. Hum. Reprod., September 1, 2002; 8(9): 817 - 822.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
E. A. McLaughlin, J. Frayne, G. Bloomerg, and L. Hall
Do fertilin {beta} and cyritestin play a major role in mammalian sperm-oolemma interactions? A critical re-evaluation of the use of peptide mimics in identifying specific oocyte recognition proteins
Mol. Hum. Reprod., April 1, 2001; 7(4): 313 - 317.
[Abstract] [Full Text] [PDF]

Home page
 Mol Hum ReprodHome page
J. A. Jury, A. C.F. Perry, and L. Hall
Identification, sequence analysis and expression of transcripts encoding a putative metalloproteinase, eMDC II, in human and macaque epididymis
Mol. Hum. Reprod., December 1, 1999; 5(12): 1127 - 1134.
[Abstract] [Full Text] [PDF]


Disclaimer:
Please note that abstracts for content published before 1996 were created through digital scanning and may therefore not exactly replicate the text of the original print issues. All efforts have been made to ensure accuracy, but the Publisher will not be held responsible for any remaining inaccuracies. If you require any further clarification, please contact our Customer Services Department.