Molecular Human Reproduction, Vol. 7, No. 6, 521-543,
June 2001
© 2001 European Society of Human Reproduction and Embryology
Embryology |
A set of 840 mouse oocyte genes with well-matched human homologues
Department of Anatomy and Structural Biology, University of Otago, Medical School, P.O.Box 913, Dunedin, New Zealand
Abstract
GenBank contains 14 477 expressed sequence tags (EST) derived from mouse oocyte cDNA libraries: 3499 of these are from two unfertilized oocyte libraries and 10 978 are from two fertilized oocyte libraries. Gene expression profiles were obtained for these libraries by matching library EST to UniGene clusters. The 14 477 EST identified 4226 UniGenes. These were screened using HomoloGene to identify 1386 homologous UniGene clusters in two other species with one of the matches being human. Within these human matches, 840 encoded named proteins, 223 encoded hypothetical proteins, and 323 encoded clustered EST. The set of named genes provides the first step in establishing a database of genes expressed in mouse oocytes and, by extension, human oocytes.
gene expression/HomoloGene/human homologues/oocytes/UniGene
Notes
1 To whom correspondence should be addressed. E-mail: david.green{at}stonebow.otago.ac.nz
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