Erratum
for Huminiecki et al., Mol. Hum. Reprod. 7 (3) 255-264.
Molecular Human Reproduction, Vol. 7, No. 5, 495,
May 2001
© 2001 European Society of Human Reproduction and Embryology
Vascular endothelial growth factor transgenic mice exhibit reduced male fertility and placental rejection
L. Huminiecki,
H.Y. Chan,
S. Liu,
R. Poulsom,
G. Stamp,
A.L. Harris and
R. Bicknell
Figure 6
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Figure 6. Spermiogenic arrest and seminiferous tubule disorganization in muc1-VEGF (121 isoform) transgenic mice. (Top) Haematoxylin and eosin stain of wild type seminiferous tubule showing good organization with large peripheral spermatogonia, a dense palisaded layer of spermatocytes and spermatids and mature spermatozoa in the lumen of the tubule (left). Feulgen stain (centre) highlights the spermatozoa and renders them easier to identify. The epididymal tubules (right) contain only mature spermatozoa. (Middle) Transgenic seminiferous tubule showing a disorganized structure with few spermatocytes or spermatogonia: Johnsen score 4 (left). The absence of spermatozoa was confirmed by Feulgen staining (centre). The epididymal tubules contained few spermatozoa and large amounts of cellular debris (right). (Lower) by Feulgen staining (centre). The epididymal tubules contained few spermatozoa and large amounts of cellular debris (right). (Lower) Seminiferous tubules with decreasing levels of maturation and increasing disorganization (Johnsen scores 8, 7 and 6 from left to right).
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